I know this video is a little long, but it is very interesting. The speaking in the beginning sets the tone for the short very precisely. The two lights, equalling the two characters we see throughout the short. And then at the end, when all the lights are swirling around her, made me humble. It's the fact that everyone dies, and that there is no need to be afraid of death.
Also, I think there is a lot to be said about the fact that this is in cartoon, and not acted out by real people. I think it's because people relate more to cartoons than real people, and this concept is very relatable to everyone.